Biomolecular & Cellular Dynamics Lab.
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Global Research Lab #

We aim to visualize the dynamic progressions of ensemble DNA mismatch repair (MMR) in vitro and in vivo to detail the mechanism of MMR using single-molecule techniques, and then develop a platform to screen MMR functions of a single cell at the single-molecule level, which will make it possible to overcome the heterogeneity problem of cancer cells for precision medicine.

PI: Prof. Jong-Bong Lee
Partner Investigator: Prof. Jae-Hyung Jeon (POSTECH)
Foreign PI: Prof. Richard Fishel (Ohio State University)

This research is supported by Global Research Lab Program through the National Research Foundation of Korea funded by the Ministry of Science and ICT.